Domperidone and Ventricular Arrhythmia or Sudden Cardiac Death

  title={Domperidone and Ventricular Arrhythmia or Sudden Cardiac Death},
  author={C. Noord and J. Dieleman and G. Herpen and K. Verhamme and iriam C. J. M. Sturkenboom},
  journal={Drug Safety},
  • C. Noord, J. Dieleman, +2 authors iriam C. J. M. Sturkenboom
  • Published 2010
  • Medicine
  • Drug Safety
  • AbstractBackground: Recently, a 4-fold increase in risk of sudden cardiac death (SCD) was reported for domperidone in a study that focused on corrected QT interval (QTc)-prolonging drugs as a class and their association with SCD. Objective: To evaluate the association between the use of domperidone and serious non-fatal ventricular arrhythmia (VA) and SCD in the general population. Methods: We performed a population-based, case-control study during 1996–2007 in the Integrated Primary Care… CONTINUE READING
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