Domperidone Treatment for Gastroparesis: Demographic and Pharmacogenetic Characterization of Clinical Efficacy and Side-Effects

@article{Parkman2010DomperidoneTF,
  title={Domperidone Treatment for Gastroparesis: Demographic and Pharmacogenetic Characterization of Clinical Efficacy and Side-Effects},
  author={H. Parkman and M. Jacobs and A. Mishra and Jessica A. Hurdle and P. Sachdeva and J. Gaughan and Evgeny Krynetskiy},
  journal={Digestive Diseases and Sciences},
  year={2010},
  volume={56},
  pages={115-124}
}
  • H. Parkman, M. Jacobs, +4 authors Evgeny Krynetskiy
  • Published 2010
  • Biology, Medicine
  • Digestive Diseases and Sciences
  • BackgroundDomperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability. Effectiveness and side-effects from domperidone may be influenced by patient-related factors including polymorphisms in genes encoding drug-metabolizing enzymes, drug transporters, and domperidone targets.AimsThe aim of this study was to determine if demographic and pharmacogenetic parameters of patients receiving domperidone are associated with response to treatment or… CONTINUE READING
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