Domperidone: A Peripherally Acting Dopamine2-Receptor Antagonist

  title={Domperidone: A Peripherally Acting Dopamine2-Receptor Antagonist},
  author={J. Barone},
  booktitle={The Annals of pharmacotherapy},
  • J. Barone
  • Published in The Annals of pharmacotherapy 1999
  • Medicine
  • OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and safety of domperidone in the treatment of gastrointestinal motility disorders and emesis. DATA SOURCES: MEDLINE and Excerpta Medica online databases were searched to identify published reports. STUDY SELECTION: Domperidone has been marketed worldwide outside the US since 1978, and extensive clinical data for this drug are available. This review focuses on the clinical experience from controlled studies of domperidone in the… CONTINUE READING
    209 Citations

    Paper Mentions

    Interventional Clinical Trial
    The purpose of this study is to prescribe oral domperidone for subjects with gastrointestinal disorders who have failed or suffered adverse effects from standard medical treatment.  
    Interventional Clinical Trial
    The purpose of this study is to make Domperidone available to patients with gastrointestinal disorders who have failed standard therapy and who might benefit from it.  
    ConditionsChronic Idiopathic Constipation, Dyspepsia, Esophagitis, (+4 more)
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