Domino paired kidney donation: a strategy to make best use of live non-directed donation

  title={Domino paired kidney donation: a strategy to make best use of live non-directed donation},
  author={Robert A. Montgomery and Sommer E Gentry and William H. Marks and Daniel S Warren and Janet M. Hiller and Julie A. Houp and Andrea A. Zachary and Joseph Melancon and Warren R. Maley and Hamid Rabb and Christopher E. Simpkins and Dorry L. Segev},
  journal={The Lancet},
Expanding the live kidney donor pool: ethical considerations regarding altruistic donors, paired and pooled programs.
Ethical issues surrounding the various methods of expanding the donor pool, including altruistic donation as well as paired and pooled exchange programs, are explored.
Kidney paired donation: a plea for a Swiss National Programme.
This review is a plea for implementing a national kidney paired donation programme in Switzerland, able to facilitate kidney transplantation in 49% of registered incompatible pairs.
Strategies to expand the living donor pool for kidney transplantation.
In the opinion logistic solutions like paired exchange, list exchange and altruistic donation programs are to be preferred over the more medical demanding programs e.g. desensitization and transplantation across the blood type barrier.
The application of paired donation to live donor liver transplantation
  • D. Segev, R. Montgomery
  • Medicine
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • 2010
The last decade has seen substantial growth and expansion of kidney paired donation (KPD), a modality by which pairs of incompatible live kidney donors and their intended recipients exchange kidneys
Kidney paired donation.
  • C. B. Wallis, K. Samy, A. Roth, M. Rees
  • Medicine
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2011
A basic overview of the concepts and challenges faced by KPD are provided as the emerging national KPD system in the USA prepares for a national pilot program with the United Network for Organ Sharing.
The non-directed living kidney donor: Why donate to strangers?
Qualitative analyses suggest that non-directed living kidney donors think deeply about their decision and have a resolve to help others that is aligned with their values.
Clinical Outcomes of Multicenter Domino Kidney Paired Donation
  • Y. J. Lee, S. Lee, D. J. Kim
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2009
In conclusion, multicenter domino KPD could multiply the benefits of donation from LNDs, with patients and graft survival rates comparable to those seen with conventional KPD.
Kidney paired donation: fundamentals, limitations, and expansions.
This review article details how several impediments to Kidney paired donation have been overcome to the benefit of ever greater numbers of patients.
Utilization and Outcomes of Kidney Paired Donation in the United States
The results suggest that full utilization of KPD would encourage registration of and improve matching for patients who are more difficult to identify and match and reduce travel requirements and thereby improve access to this treatment modality.
Kidney paired donation: principles, protocols and programs.
The article focuses on the recent progresses in KPD and it also reviews some of the differences and commonalities across four different national KPD programs.


Clinical results from transplanting incompatible live kidney donor/recipient pairs using kidney paired donation.
This series of patients who received transplants from a single-center KPD pool provides evidence that recipients with incompatible live donors, even those with rare blood type combinations or high degrees of HLA antigen sensitization, can receive transplants through KPD with graft survival rates that appear to be equivalent to directed, compatible live donor transplants.
The Dutch National Living Donor Kidney Exchange Program
The living donor kidney exchange program is a successful approach that does not harm any of the candidates on the deceased donor kidney waitlist and should be sustained for optimal results.
The nondirected live-kidney donor: ethical considerations and practice guidelines: A National Conference Report1
The suggested content of screening interviews, which provide information regarding the donation process, elicits pertinent medical and psychosocial history, and assesses NDD motivation are presented in this report and approaches to identifying the center that would evaluate the suitability of the NDD, to performing the kidney recovery, and to selecting the N DD recipient are proposed.
Donor Kidney Exchanges
  • F. Delmonico, P. Morrissey, R. Rohrer
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2004
Kidney transplantation from live donors achieves an excellent outcome regardless of human leukocyte antigen (HLA) mismatch. This development has expanded the opportunity of kidney transplantation
Characterization of Waiting Times in a Simulation of Kidney Paired Donation
A national kidney paired donation (KPD) program will substantially increase transplant opportunities for recipients with blood type incompatible or cross‐match positive donors. It seems likely that
This study replicates the 1997 findings and increases confidence that a significant minority of British Columbians support living anonymous donation and that some would consider becoming LADs themselves.
Ethics of a paired-kidney-exchange program.
This work proposes to increase the supply of organs by using kidneys from living donors who are ABO-incompatible with the intended recipients but are A BO-compatible with other recipients through an exchange arrangement.
Should all living donors be treated equally?
It is argued that voluntary donations have a degree of moral obligation based on intimacy and that intimacy allows, but does not require, that these donors take on slightly additional risk.
  • A. Spital
  • Medicine, Political Science
  • 2001
It seems that the vast majority of American adults believe that living kidney donation by friends and altruistic strangers is an acceptable practice and many would consider making such donations themselves.
Should people who donate a kidney to a stranger be permitted to choose their recipients? Views of the United States public
Public attitudes toward kidneys donated by altruistic living strangers support the current policy of several transplant centers that people who wish to donate a kidney to a stranger are not permitted to choose their recipients on the basis of membership in a racial or religious group.