Dominant social status facilitates the behavioral effects of serotonergic agonists

  title={Dominant social status facilitates the behavioral effects of serotonergic agonists},
  author={Michael J. Raleigh and Gary L. Brammer and Michael T. Mcguire and Arthur Yuwiler},
  journal={Brain Research},
Effects of fluoxetine on play dominance in juvenile rats
The results indicate that fluoxetine can reduce the playful pins of juvenile rats, but that prior social learning mediates the strength of these effects.
Effects of the Selective Serotonin Reuptake Inhibitor Fluoxetine on Social Behaviors in Male and Female Prairie Voles (Microtus ochrogaster)
The findings suggest that serotonin influences social behavior in prairie voles, and fluoxetine did not alter nonsocial behaviors.
Time-dependent effects of PCPA on social aggression in chicks
Ethopharmacological studies differentiate the effects of various serotonergic compounds on aggression in rats
The discussion attempts to delineate a role for 5‐HT receptor subtype involvement in the modulation of aggression, with the restrictions faced with regard to the lack of specific serotonergic agonists and antagonists for certain receptor subtypes.
The social competition test as an animal model of anxiety in triads of male wistar rats.
Results indicate that priority of access was indeed socially mediated although individual palatability and skill probably also contributed to the success of each rank position, consistent with previous findings that the social competition test appears sensitive to a range of anxiolytic and anxiogenic drug treatments but not to chronic antidepressant drug or repeated ECS treatment.
Rodent models of aggressive behavior and serotonergic drugs
  • B. Olivier, J. Mos
  • Psychology, Biology
    Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • 1992
Differential behavioral effects of tryptophan and 5-hydroxytryptophan in vervet monkeys: influence of catecholaminergic systems
  • M. Raleigh
  • Biology, Psychology
  • 2005
5-HTP's effects on catecholaminergic systems may underlie the differing behavioral effects of tryptophan and 5- HTP on behavior in a species closely related to humans.
Serotonin, Social Behaviour, and Aggression in Vervet Monkeys
In this work, studies of the psychopharmacology of aggression are greatly enhanced by investigating animals or humans living in social groups, and pharmacological studies designed within this paradigm result in new types of data and interpretations different from findings and conclusions developed using isolated or paired animals.


Sociopharmacology of d-amphetamine in Macaca arctoides
Ethanol, Methamphetamine, Pentobarbital
Significant dose-response curves for social behaviors after single-dose administration of drugs in five adult male monkeys living in their "home" troop of about 30 animals are found and may help to clarify some controversies arising from conflicting data in studies of drug effects on humans.
Primate social behavior as a method of analysis of drug action: studies with THC in monkeys
Current observations of effects of acute and long-term chronic administration of delta9-tetrahydrocannabinol in group-caged rhesus monkeys are cited to demonstrate the sensitivity and specificity of primate social behavior test systems in characterization of CNS drugs.
A primate analogue of amphetamine-induced behaviors in humans.
During amphetamine administration, there was a significant increase in the following behaviors: time spent in "sit tense" postures, frequency of orienting, and frequency of agonistic behaviors.
Discriminative stimulus properties of quipazine: mediation by serotonin2 binding sites.
The results suggest that the quipazine cue is mediated by an action at central 5-HT2 sites, and not on the behavioral measure or affinities for the5-HT1 site.