Dominant role of thyrotropin-releasing hormone in the hypothalamic-pituitary-thyroid axis.

Abstract

Hypothalamic thyrotropin-releasing hormone (TRH) stimulates thyroid-stimulating hormone (TSH) secretion from the anterior pituitary. TSH then initiates thyroid hormone (TH) synthesis and release from the thyroid gland. Although opposing TRH and TH inputs regulate the hypothalamic-pituitary-thyroid axis, TH negative feedback is thought to be the primary… (More)

Topics

Cite this paper

@article{Nikrodhanond2006DominantRO, title={Dominant role of thyrotropin-releasing hormone in the hypothalamic-pituitary-thyroid axis.}, author={Amisra A Nikrodhanond and T{\^a}nia Maria Ortiga-Carvalho and Nobuyuki Shibusawa and Koshi Hashimoto and Xiao Hui Liao and Samuel Refetoff and M Yamada and Masatomo Mori and Fredric E. Wondisford}, journal={The Journal of biological chemistry}, year={2006}, volume={281 8}, pages={5000-7} }