Dominant optic atrophy. The clinical profile.

@article{Kline1979DominantOA,
  title={Dominant optic atrophy. The clinical profile.},
  author={Lanning B. Kline and Joel S. Glaser},
  journal={Archives of ophthalmology},
  year={1979},
  volume={97 9},
  pages={1680-6}
}
We examined 24 individuals in four family pedigrees with dominantly inherited optic atrophy (DOA); 12 patients met the criteria for diagnosis of DOA and two were suspect. Our data indicate that (1) insidious onset usually occurred in childhood, but subjective visual symptoms may evolve in adulthood; (2) visual function was minimally (20/25) to moderately (20/400) abnormal, could be strikingly asymmetric in an individual (eg, 20/30 in the right eye and 20/200 in the left eye), and showed… CONTINUE READING

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