Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking

@article{Galea2013DomainSA,
  title={Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking},
  author={C. Galea and H. M. Nguyen and K. George Chandy and Brian J. Smith and R. Norton},
  journal={Cellular and Molecular Life Sciences},
  year={2013},
  volume={71},
  pages={1191-1210}
}
  • C. Galea, H. M. Nguyen, +2 authors R. Norton
  • Published 2013
  • Medicine, Biology
  • Cellular and Molecular Life Sciences
  • MMP23 is a member of the matrix metalloprotease family of zinc- and calcium-dependent endopeptidases, which are involved in a wide variety of cellular functions. Its catalytic domain displays a high degree of structural homology with those of other metalloproteases, but its atypical domain architecture suggests that it may possess unique functional properties. The N-terminal MMP23 pro-domain contains a type-II transmembrane domain that anchors the protein to the plasma membrane and lacks the… CONTINUE READING
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