Dolphins as animal models for type 2 diabetes: sustained, post-prandial hyperglycemia and hyperinsulinemia.

@article{VennWatson2011DolphinsAA,
  title={Dolphins as animal models for type 2 diabetes: sustained, post-prandial hyperglycemia and hyperinsulinemia.},
  author={Stephanie K. Venn-Watson and Kevin J. Carlin and Sam H Ridgway},
  journal={General and comparative endocrinology},
  year={2011},
  volume={170 1},
  pages={193-9}
}
There is currently no known natural animal model that fully complements type 2 diabetes in humans. Criteria for a true natural animal model include the presence of a fasting hyperglycemia, evidence of insulin resistance, and pathologies matching that reported in humans. To investigate the bottlenose dolphin (Tursiops truncatus) as a comparative model for type 2 diabetes in humans, hourly plasma and urine chemistry changes, including glucose, were analyzed among five healthy, adult dolphins for… CONTINUE READING
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