Doing the MATH: is the mouse a good model for fly development?

@article{Hassan2000DoingTM,
  title={Doing the MATH: is the mouse a good model for fly development?},
  author={Bassem A Hassan and Hugo J. Bellen},
  journal={Genes & development},
  year={2000},
  volume={14 15},
  pages={
          1852-65
        }
}
Members of the superfamily of basic helix–loop–helix (bHLH) proteins have been shown to play important roles in neurogenesis in many species. Neuronal bHLH proteins can be divided into two families: the Achaete– Scute complex (AS-C) related proteins and the Atonalrelated proteins, or ARPs. In this review we discuss the ARPs, focusing on their functional diversity within each organism and contrasting it with the remarkable conservation of some of the functions across species. In reviewing the… CONTINUE READING

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