Dogs with Cognitive Dysfunction as a Spontaneous Model for Early Alzheimer's Disease: A Translational Study of Neuropathological and Inflammatory Markers.

@article{Schtt2016DogsWC,
  title={Dogs with Cognitive Dysfunction as a Spontaneous Model for Early Alzheimer's Disease: A Translational Study of Neuropathological and Inflammatory Markers.},
  author={Trine Sch{\"u}tt and Lone Helboe and Lars \Ostergaard Pedersen and Gunhild Waldemar and Mette Berendt and J. T. Pedersen},
  journal={Journal of Alzheimer's disease : JAD},
  year={2016},
  volume={52 2},
  pages={433-49}
}
Aged companion dogs with canine cognitive dysfunction (CCD) spontaneously develop varying degrees of progressive cognitive decline and particular neuropathological features correspondent to the changes associated with Alzheimer's disease (AD) in humans. The aim of the present study was to characterize certain aspects of neuropathology and inflammatory markers related to aging and CCD in dogs in comparison with human AD. Fifteen brains from aged dogs with normal cognitive function, mild… CONTINUE READING
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