Dog vaccination with EgM proteins against Echinococcus granulosus

  title={Dog vaccination with EgM proteins against Echinococcus granulosus},
  author={Zhuang-Zhi Zhang and Gang Guo and Jun Li and Baoxin Shi and Li Zhao and Baoping Guo and Xu Zhang and Jun-Wei Wang and Xueting Zheng and Wenjing Qi and Li He and Wenbao Zhang},
  journal={Infectious Diseases of Poverty},
BackgroundDogs play a pivotal role in the transmission of cystic echinococcosis (CE), a zoonosis caused by the tapeworm Echinococcus granulosus. We showed previously that dogs vaccinated with two E. granulosus adult-worm specific proteins, EgM9 and EgM123, emulsified with Freund’s adjuvants induced significant protective efficacy in terms of reduction in worm burden and egg production after 45 days post-infection. It was not known whether this protection can be sustained using adjuvants… 
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