Does zonal aganglionosis really exist? Report of a rare variety of Hirschsprung's disease and review of the literature.

@article{Yunis1983DoesZA,
  title={Does zonal aganglionosis really exist? Report of a rare variety of Hirschsprung's disease and review of the literature.},
  author={Edomond J. Yunis and William K Sieber and D R Akers},
  journal={Pediatric pathology},
  year={1983},
  volume={1 1},
  pages={33-49}
}
The aganglionic segment of intestine in Hirschsprung's disease begins at the anus and extends proximally for a distance that varies from case to case. Occasional reports describe patients in whom the aganglionosis is segmental, with normal distal innervation or a skip area of normal innervation within an area of aganglionosis. This paper describes 4 patients with Hirschsprung's disease wherein a segment of normally innervated colon was found in an otherwise aganglionic colon. Two of these… CONTINUE READING

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