• DOI:10.1096/fasebj.13.9.1007
Corpus ID: 15426564

Does vitamin C act as a pro‐oxidant under physiological conditions?

@article{Carr1999DoesVC,
  title={Does vitamin C act as a pro‐oxidant under physiological conditions?},
  author={A. Carr and B. Frei},
  journal={The FASEB Journal},
  year={1999},
  volume={13},
  pages={1007 - 1024}
}

A. Carr, B. Frei

Published 1999

Medicine, Biology

The FASEB Journal

Vitamin C readily scavenges reactive oxygen and nitrogen species and may thereby prevent oxidative damage to important biological macromolecules such as DNA, lipids, and proteins. [...] Key Method To examine this issue, we reviewed studies that investigated the role of vitamin C, both in the presence and absence of metal ions, in oxidative DNA, lipid, and protein damage. We found compelling evidence for antioxidant protection of lipids by vitamin C in biological fluids, animals, and humans, both with and…Expand Abstract

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