Does tolerance develop to the anxiolytic effects of septal lesions?

Abstract

Previous studies have shown that septal lesions produce anxiolytic-like effects in tests of rat "anxiety" (i.e., septal lesions increase open-arm exploration in the elevated plus-maze test and decrease burying in the shock-probe burying test). The present experiment examined whether "tolerance" develops to the anxiolytic effects of septal lesions, in a… (More)

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