Does the respiratory system limit exercise in mild chronic obstructive pulmonary disease?

@article{Chin2013DoesTR,
  title={Does the respiratory system limit exercise in mild chronic obstructive pulmonary disease?},
  author={Roberto C. Chin and Jordan A. Guenette and Sicheng Cheng and Natya Raghavan and Naparat Amornputtisathaporn and Arturo Cort{\'e}s-T{\'e}lles and Katherine Alexandra Webb and Denis O'donnell},
  journal={American journal of respiratory and critical care medicine},
  year={2013},
  volume={187 12},
  pages={1315-23}
}
RATIONALE It is not known if abnormal dynamic respiratory mechanics actually limit exercise in patients with mild chronic obstructive pulmonary disease (COPD). We reasoned that failure to increase peak ventilation and Vt in response to dead space (DS) loading during exercise would indicate true ventilatory limitation to exercise in mild COPD. OBJECTIVES To compare the effects of DS loading during exercise on ventilation, breathing pattern, operating lung volumes, and dyspnea intensity in… CONTINUE READING

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A comparison of the mechanical and sensory consequences of dead space loading during exercise in mild COPD and in health [abstract

  • R Chin, JA Guenette, +5 authors DE. O’Donnell
  • Am J Respir Crit Care Med 2012;185:A1547
  • 2012
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