Does the dynamic Stokes shift report on slow protein hydration dynamics?

@article{Halle2009DoesTD,
  title={Does the dynamic Stokes shift report on slow protein hydration dynamics?},
  author={Bertil Halle and Lennart Nilsson},
  journal={The journal of physical chemistry. B},
  year={2009},
  volume={113 24},
  pages={8210-3}
}
The time-dependent fluorescence frequency shift of protein-attached probes has a much slower decay than that for the free probe. The decay times, ranging from 10 ps to several nanoseconds, have been attributed to hydration water motions several orders of magnitude slower than those in the hydration shell of small solutes. This interpretation deviates strongly from the prevailing picture of protein hydration dynamics. We argue here that the slow decay in the fluorescence shift can be explained… CONTINUE READING

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