Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial
@article{Svendsen2004DoesTC, title={Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial}, author={Kristina Bacher Svendsen and Troels Staehelin Jensen and Flemming Winther Bach}, journal={BMJ : British Medical Journal}, year={2004}, volume={329}, pages={253} }
Abstract Objective To evaluate the effect of the oral synthetic δ-9-tetrahydrocannabinol dronabinol on central neuropathic pain in patients with multiple sclerosis. Design Randomised double blind placebo controlled crossovertrial. Setting Outpatient clinic, University Hospital of Aarhus, Denmark. Participants 24 patients aged between 23 and 55 years with multiple sclerosis and central pain. Intervention Orally administered dronabinol at a maximum doseof 10 mg daily or corresponding placebo for…
443 Citations
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The researchers reported that dronabinol had a significant analgesic effect on central pain in patients with multiple sclerosis, although the effects were modest they were clinically relevant.
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