Does the addition of lamivudine to peginterferon α-2a sustain response rates in HBeAg-negative hepatitis B?

Abstract

DESIGN AND INTERVENTION This multicenter, partially double-blind study recruited adults with chronic hepatitis B who were negative for HBeAg and positive for antiHBe antibody and hepatitis B surface antigen (HBsAg) for at least 6 months. Eligible patients had an HBV DNA level of >100,000 copies/ ml and a serum alanine aminotransferase level >1 but ≤10 times… (More)
DOI: 10.1038/ncpgasthep0068

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