Does the addition of dexamethasone to standard therapy for acute migraine headache decrease the incidence of recurrent headache for patients treated in the emergency department? A meta-analysis and systematic review of the literature.

@article{Singh2008DoesTA,
  title={Does the addition of dexamethasone to standard therapy for acute migraine headache decrease the incidence of recurrent headache for patients treated in the emergency department? A meta-analysis and systematic review of the literature.},
  author={Amandeep Singh and Harrison J. Alter and Brita E. Zaia},
  journal={Academic emergency medicine : official journal of the Society for Academic Emergency Medicine},
  year={2008},
  volume={15 12},
  pages={1223-33}
}
OBJECTIVES Neurogenic inflammation is thought to play a role in the development and perpetuation of migraine headache. The emergency department (ED) administration of dexamethasone in addition to standard antimigraine therapy has been used to decrease the incidence of recurrent headaches at 24 to 72 hours following evaluation. This systematic review details the completed trials that have evaluated the use of dexamethasone in this role. METHODS The authors searched MEDLINE, EMBASE, CINAHL… CONTINUE READING