Does the addition of clomiphene citrate or letrazole to gonadotropin treatment enhance the oocyte yield in poor responders undergoing IVF?

@article{Jovanovic2011DoesTA,
  title={Does the addition of clomiphene citrate or letrazole to gonadotropin treatment enhance the oocyte yield in poor responders undergoing IVF?},
  author={Vuk P. Jovanovic and Daniel H. Kort and Michael M. Guarnaccia and Mark V. Sauer and Rog{\'e}rio Souza Lobo},
  journal={Journal of Assisted Reproduction and Genetics},
  year={2011},
  volume={28},
  pages={1067-1072}
}
To evaluate the effect of adjunctive letrazole or clomiphene in IVF stimulation protocols. A retrospective analysis of high dose GnRH antagonist IVF cycles (450–600 IU of gonadotropins) that have met poor responder criteria. Selected consecutive cycles in same patients differed solely in presence or absence of adjunctive clomiphene or letrazole. Supplementation with clomiphene citrate in poor responders showed significant improvements (p < 0.05) in estradiol levels (1506 vs. 1044 pg/ml), number… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 21 references

a systematic review of the literature

  • Polyzos NP et al. Aromatase inhibitors for female infertility
  • Reprod Biomed Online. 2009;19(4):456–71. 1072 J…
  • 2011
1 Excerpt

Letrozole can be used in combination with GnRH agonists in poor responders without negating its beneficial effects

  • M Kapoor
  • Fertil Steril. 2008;90(Supplement 1):S34–4
  • 2008

Letrozole in combination with gonadotropins improves implantation rates, ongoing pregnancy rates and decreases cancellation rates in poor responders

  • M Kapoor
  • Fertil Steril. 2008;90(Supplement 1):S33–4
  • 2008

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