Does the PI3K pathway play a role in basal breast cancer?

Abstract

Many cell kinases exert their proliferative and pro-survival effects through activation of the phosphatidylinositol 3-kinase (PI3K)-Akt pathway. Basal-like breast cancer is a subtype that can be identified by molecular analysis and often includes tumors lacking expression of estrogen receptor/progesterone receptor or human epidermal growth factor receptor… (More)

DOI: 10.3816/CBC.2010.s.014

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