Does the Heart’s Hormone, ANP, Help in Congestive Heart Failure?

Abstract

In congestive hearf failure, increased secretion of afrial nafriurefic pepfide (ANP) is an important compensatory mechanism that unloads the failing heart and promofes renal salt and wafer excretion. However, acfivafion of opposing sodium-refaining facfors, parficularly the renin-angiofensin sysfem, reduces renal responsiveness to A NP and shifts the… (More)

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