Does the Agent of Scrapie Replicate without Nucleic Acid ?

  title={Does the Agent of Scrapie Replicate without Nucleic Acid ?},
  author={T. Alper and W. Cramp and D. Haig and M. Clarke},
  • T. Alper, W. Cramp, +1 author M. Clarke
  • Published 1967
  • Biology, Medicine
  • Nature
  • Scrapie is a slowly developing disease of the nervous system. Experiments on the effects of ultra-violet irradiation of suspensions of infected mouse brain extracts confirm that the agent responsible for it does not depend on a nucleic acid for its ability to replicate. No evidence is obtained, however, to indicate whether the agent is associated with a protein. 
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