Does stimulant therapy of attention‐deficit/hyperactivity disorder beget later substance abuse?

@article{Wilens2003DoesST,
  title={Does stimulant therapy of attention‐deficit/hyperactivity disorder beget later substance abuse?},
  author={Timothy E Wilens and Stephen V. Faraone and Joseph Biederman and Samantha C Gunawardene},
  journal={Journal of Developmental \& Behavioral Pediatrics},
  year={2003},
  volume={24},
  pages={210}
}
OBJECTIVE Concerns exist that stimulant therapy of youths with attention-deficit/hyperactivity disorder (ADHD) may result in an increased risk for subsequent substance use disorders (SUD). We investigated all long-term studies in which pharmacologically treated and untreated youths with ADHD were examined for later SUD outcomes. METHODS A search of all available prospective and retrospective studies of children, adolescents, and adults with ADHD that had information relating childhood… Expand
ADHD, stimulant treatment in childhood and subsequent substance abuse in adulthood - a naturalistic long-term follow-up study.
TLDR
The results warrant increased focus on the possibly increased risk of substance abuse in females with ADHD compared to males with ADHD, and female gender, conduct disorder in childhood and older age at initiation of stimulant treatment increased the risk of later SUD and alcohol abuse. Expand
Stimulant therapy and risk for subsequent substance use disorders in male adults with ADHD: a naturalistic controlled 10-year follow-up study.
TLDR
The findings revealed no evidence that stimulant treatment increases or decreases the risk for subsequent substance use disorders in children and adolescents with ADHD when they reach young adulthood. Expand
Does Early Exposure to Stimulants Lead to Substance Use Disorders Later on?
Attention deficit/hyperactivity disorder (ADHD) denotes childhood problems of hyperactivity, inattention, and impulsivity, leading to impairments in daily functioning, scholastic performance, andExpand
A Prospective Examination of the Association of Stimulant Medication History and Drug Use Outcomes among Community Samples of ADHD Youths
TLDR
The results from a community-based sample extend the growing body of literature based on clinically derived samples indicating that stimulant treatment does not create a significant risk for subsequent substance use disorders. Expand
A naturalistic study of the effects of pharmacotherapy on substance use disorders among ADHD adults
TLDR
The results are consistent across substances and ADHD diagnoses, and support the hypothesis that pharmacotherapy does not cause subsequent SUDs. Expand
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TLDR
It appears that ADHD pharmacotherapy does not increase the risk for SUD, and medication treatment alone does not appear to be particularly effective in treating SUD in currently active substance abusing individuals with ADHD. Expand
Long-Term Use of Stimulants in Children with Attention Deficit Hyperactivity Disorder
TLDR
Children with ADHD treated with stimulants for as long as 2 years continue to benefit from the treatment, with improvements observed in ADHD symptoms, comorbid oppositional defiant disorder, and academic and social functioning, with no significant problems of tolerance or adverse effects. Expand
The clinical dilemma of using medications in substance-abusing adolescents and adults with attention-deficit/hyperactivity disorder: what does the literature tell us?
TLDR
Treating ADHD pharmacologically in individuals with ADHD plus SUD has a moderate impact on ADHD and SUD that is not observed in controlled trials and does not result in worsening of SUD or adverse interactions specific to SUD. Expand
Effect of prior stimulant treatment for attention-deficit/hyperactivity disorder on subsequent risk for cigarette smoking and alcohol and drug use disorders in adolescents.
TLDR
Stimulant therapy does not increase but rather reduces the risk for cigarette smoking and SUDs in adolescents with ADHD, and there were no differences in SUD risk factors between naturalistically treated and untreated groups. Expand
Childhood stimulant treatment and risk for later substance abuse.
TLDR
This study found that stimulant therapy for attention-deficit/hyperactivity disorder in childhood is not associated with increased risk of adolescent experimentation with substance use, frequency of such use, or the risk of developing psychoactive substance use disorders by young adulthood. Expand
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