Does selegiline modify the progression of early Parkinson's disease? Results from a five-year study. The Norwegian-Danish Study Group.

@article{Larsen1999DoesSM,
  title={Does selegiline modify the progression of early Parkinson's disease? Results from a five-year study. The Norwegian-Danish Study Group.},
  author={Jan P. Larsen and Jasper Boas and Jesper Erdal},
  journal={European journal of neurology},
  year={1999},
  volume={6 5},
  pages={
          539-47
        }
}
The objective of this study was to examine the effect of long-term treatment with selegiline on the progression of Parkinson's disease (PD). One hundred and sixty-three patients with early PD were treated with levodopa and benserazide, combined with selegiline or placebo in a five-year randomized, placebo-controlled, double-blind, parallel group study followed by a one-month wash-out of selegiline or placebo. The main outcome measures were assessments of the severity of parkinsonism, levodopa… CONTINUE READING
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