Does schizophrenia result from developmental or degenerative processes?

  title={Does schizophrenia result from developmental or degenerative processes?},
  author={Susannah M Church and David Cotter and Elvira Bramon and Robin MacGregor Murray},
  journal={Journal of neural transmission. Supplementum},
The debate as to whether schizophrenia is a neurodevelopmental or a neurodegenerative disorder has its roots in the latter part of the 19th century when authorities such as Clouston (1891) posited that at least some insanities were "developmental" in origin. These views were soon eclipsed by Kraepelin's (1896) concept of dementia praecox as a degenerative disease, and the latter view carried not only the day but also much of the 20th century. Then, in the 1980s several research groups again… CONTINUE READING


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