Does reduction in immunosuppression in viremic patients prevent BK virus nephropathy in de novo renal transplant recipients? A prospective study.

@article{Almras2008DoesRI,
  title={Does reduction in immunosuppression in viremic patients prevent BK virus nephropathy in de novo renal transplant recipients? A prospective study.},
  author={Cyrielle Alm{\'e}ras and Vincent Foulongne and Val{\'e}rie Garrigue and Ilan Szwarc and Fernando Vetromile and Michel Segondy and Georges Mourad},
  journal={Transplantation},
  year={2008},
  volume={85 8},
  pages={1099-104}
}
BACKGROUND BK virus nephropathy (BKVN) is a severe complication of renal transplantation, resulting in graft loss in >50% of cases. Because patients with BKV viremia are at high risk for developing BKVN, the aim of our study was to analyze whether early reduction of immunosuppression (IS) could prevent BKVN in viremic patients. METHODS BKV viruria was prospectively screened every 3 months by real-time polymerase chain reaction during the first year after transplantation in 123 consecutive… CONTINUE READING