Does rapid oligomerization of hepatitis B envelope proteins play a role in resistance to proteasome degradation and enhance chronicity?

Abstract

This review discusses the nature of hepatitis B and C chronicity from a virological perspective. Work described in the literature and our in vitro studies of HBV polypeptide morphogenesis lead us to speculate about a role for HBsAg complex formation in immune evasion that may be especially important during the initial period of infection. Briefly, although… (More)

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@article{Block2006DoesRO, title={Does rapid oligomerization of hepatitis B envelope proteins play a role in resistance to proteasome degradation and enhance chronicity?}, author={Timothy M. Block and Anand Mehta and Baruch S. Blumberg and Raymond A. Dwek}, journal={DNA and cell biology}, year={2006}, volume={25 3}, pages={165-70} }