Does prophylaxis-delay in bipolar disorder influence outcome? Results from a long-term study of 147 patients.

@article{Baethge2003DoesPI,
  title={Does prophylaxis-delay in bipolar disorder influence outcome? Results from a long-term study of 147 patients.},
  author={Christopher Baethge and Michael N. Smolka and Philipp Gruschka and Anne Berghoefer and Peter Schlattmann and Michael Bauer and Lori A Altshuler and Paul Grof and Bruno Mueller-Oerlinghausen},
  journal={Acta psychiatrica Scandinavica},
  year={2003},
  volume={107 4},
  pages={260-7}
}
OBJECTIVE This study investigated the impact of latency (the time between illness onset and initiation of prophylactic treatment) on the outcome of prophylaxis in bipolar disorders. METHOD The effect of prophylaxis delay (latency) on the course of illness was assessed in 147 patients. Dependent variables were: reduction of days spent in the hospital (prior to vs. during prophylaxis), time to first recurrence, and Morbidity-Index during prophylaxis (lithium or carbamazepine). Latency and other… CONTINUE READING

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