Does perioperative use of aprotinin reduce the rejection rate in heart transplant recipients?

@article{Shuhaiber2008DoesPU,
  title={Does perioperative use of aprotinin reduce the rejection rate in heart transplant recipients?},
  author={Jeffrey H. Shuhaiber and Kimberley Goldsmith and Stephen R. Large and Steven Hong-Teng Tsui},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  year={2008},
  volume={33 5},
  pages={849-55}
}
OBJECTIVE Allograft rejection continues to be one of the most common causes of mortality after heart transplantation. We investigated if perioperative use of antifibrinolytics such as aprotinin and tranexamic acid can decrease the rate of rejection after heart transplant and their effect on transfusion. METHODS A retrospective analysis was conducted on… CONTINUE READING