Does perinatal exposure to endocrine disruptors induce autism spectrum and attention deficit hyperactivity disorders? Review

@article{deCock2012DoesPE,
  title={Does perinatal exposure to endocrine disruptors induce autism spectrum and attention deficit hyperactivity disorders? Review},
  author={Marijke de Cock and Yolanda G H Maas and Margot van de Bor},
  journal={Acta Paediatrica},
  year={2012},
  volume={101}
}
Aim:  To provide an overview of studies on perinatal exposure in humans to endocrine disrupting chemicals (EDCs) in relation to autism spectrum (ASD) and attention deficit hyperactivity (ADHD) disorders. 
Foreword: Environmental chemical exposures and autism spectrum disorders: a review of the epidemiological evidence.
  • R. Etzel
  • Medicine
    Current problems in pediatric and adolescent health care
  • 2014
TLDR
Pregnancy Asperger's disorder/PDD- pregnant women are diagnosed with at least one or more of the following conditions: anxiety, depression, impulsivity, andeternal celiac disease.
Endocrine Disruptors and Autism Spectrum Disorder in Pregnancy: A Review and Evaluation of the Quality of the Epidemiological Evidence
TLDR
It is concluded that the overall strength of evidence supporting an association between prenatal exposure to EDCs and later ASD in humans remains “limited” and inconclusive.
Early-Life Environmental Toxic Influences on Neural Development
TLDR
The present chapter summarizes the susceptibility of the developing nervous system of the child to exposures to pre- and postnatal environmental factors like neurodevelopmental toxicants, psychosocial factors, and socioeconomic position and calls for an integrative approach unifying epidemiological and mechanistic studies.
Prenatal exposure to bisphenol A and hyperactivity in children: a systematic review and meta-analysis.
TLDR
It is concluded that early life BPA exposure is a presumed human hazard for the development of hyperactivity, and immediate actions should be taken to reduce exposure in pregnant women, infants and children.
Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposure and autism.
TLDR
It is suggested that improving the environment could be vital in the management of ASD, as reports highlighting neurotoxic metals as environmental risk factors in the aetiology of ASD are discussed.
Phthalates exposure and attention-deficit/hyperactivity disorder in children: a systematic review of epidemiological literature
TLDR
A systematic review of the existing literature on the association between urinary phthalate metabolite concentrations and ADHD symptoms among children by emphasizing the confounding factors and limitations and addressed the possiblephthalate mechanism insights in human body including its impact on ADHD symptoms.
The comorbidity of ADHD and autism spectrum disorder
TLDR
There are several important differences between autism spectrum disorder and ADHD, and treatment strategies for the comorbid condition will also be reviewed.
Prenatal exposure to perfluoroalkyl substances and associations with symptoms of attention-deficit/hyperactivity disorder and cognitive functions in preschool children.
TLDR
Prenatal exposure to PFASs are not associated with ADHD symptoms or cognitive dysfunctions in preschool children aged three and a half years, which is in line with the majority of studies in this area.
Impact of Bisphenol A on Gonadotropic Hormone Levels in Children with Autism Spectrum Disorders
TLDR
Evaluating association between the serum levels of hormones; follicle-stimulating (FSH), inhibin B (INHB), and estradiol (E2) and BPA in 49 ASD children revealed that BPA may cause endocrine dysfunction in ASD children.
Prenatal Exposure to Perfluoroalkyl Substances and the Risk of Autism, Attention Deficit Hyperactivity Disorder and Cerebral Palsy in Children - A Danish National Birth Cohort Study
Perfluoroalkyl Substances (PFASs) are a group of man-made fluorine-containing compounds that are used broadly in industry and commercial products since the 1950s. PFASs are very persistent in the
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