Does nitrous oxide affect coronary microcirculation? An intravital microscopic study in the canine heart.

@article{Vollmar1995DoesNO,
  title={Does nitrous oxide affect coronary microcirculation? An intravital microscopic study in the canine heart.},
  author={Brigitte Vollmar and Peter F. Conzen and Helmut Habazettl and F Adili and Klaus Peter},
  journal={Anesthesia and analgesia},
  year={1995},
  volume={80 2},
  pages={249-55}
}
The safe use of nitrous oxide, in particular in patients with coronary artery disease, has been questioned. This study was designed to determine whether nitrous oxide directly affects global coronary hemodynamic variables and coronary arteriolar microvessels in the absence of changes of myocardial oxygen consumption. In dogs the effects of nitrous oxide were evaluated during normotension (NT, intravenous [IV] piritramid, nitrogen/oxygen; and NT/N2O, IV piritramid, nitrous oxide/oxygen) and… CONTINUE READING
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