Does nitrogen dioxide exposure increase airways responsiveness?

  title={Does nitrogen dioxide exposure increase airways responsiveness?},
  author={Lawrence J Folinsbee},
  journal={Toxicology and industrial health},
  volume={8 5},
A number of reports have suggested that exposure to nitrogen dioxide (NO2) may cause increased airways responsiveness (AR). Twenty studies of asthmatics and five studies of healthy subjects exposed to NO2 were used to test this hypothesis using a simple method of meta-analysis. Individual data were obtained for the above studies and the direction of change in AR was determined for each subject. Only studies with available individual data were used. Subjects from these studies whose directional… CONTINUE READING

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