Does myeloma secrete an osteoblast inhibiting factor?

Abstract

Unlike most other tumours, myeloma causes bone destruction without an osteoblastic reaction; we tried to assess whether myeloma secretes a humoral factor that inhibits osteoblasts. Human bone-derived cells were either co-cultured with myeloma cells, or cultured in medium conditioned by myeloma cells. Bone-derived cell growth was measured by cell counts and… (More)

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@article{Evans1989DoesMS, title={Does myeloma secrete an osteoblast inhibiting factor?}, author={Carol Elizabeth Evans and Charles Bernard Galasko and C. A. Ward}, journal={The Journal of bone and joint surgery. British volume}, year={1989}, volume={71 2}, pages={288-90} }