Does midazolam alter the clinical effects of intravenous ketamine sedation in children? A double-blind, randomized, controlled, emergency department trial.

@article{Wathen2000DoesMA,
  title={Does midazolam alter the clinical effects of intravenous ketamine sedation in children? A double-blind, randomized, controlled, emergency department trial.},
  author={Joe E. Wathen and Mark G. Roback and Todd A. MacKenzie and Joan P. Bothner},
  journal={Annals of emergency medicine},
  year={2000},
  volume={36 6},
  pages={
          579-88
        }
}
STUDY OBJECTIVE This study was conducted to investigate the frequency and severity of adverse effects, specifically emergence phenomena, experienced by patients receiving intravenous ketamine with or without midazolam for sedation in a pediatric emergency department. METHODS Patients aged 4.5 months to 16 years receiving ketamine sedation were prospectively enrolled in a double-blind, randomized, controlled study at a university-affiliated children's hospital-pediatric ED. All patients… CONTINUE READING

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