Does losartan reduce the risk of stroke in patients with hypertension?

  • Thomas Unger
  • Published 2005 in Nature Clinical Practice Cardiovascular Medicine


DESIGN The LIFE study was a double-blind, randomized, multicenter investigation involving patients who had hypertension, were aged between 55 and 80 years old and had leftventricular hypertrophy detected by electrocardiography. If patients were taking β-blockers or calcium antagonists for angina pectoris, had secondary hypertension, an ejection fraction below 0.4 or heart failure, significant renal or hepatic dysfunction, only one kidney or had had a stroke or myocardial infarction within the previous 6 months, they were excluded.

DOI: 10.1038/ncpcardio0197

Cite this paper

@article{Unger2005DoesLR, title={Does losartan reduce the risk of stroke in patients with hypertension?}, author={Thomas Unger}, journal={Nature Clinical Practice Cardiovascular Medicine}, year={2005}, volume={2}, pages={236-237} }