Does long-term opioid therapy reduce pain sensitivity of patients with chronic low back pain? Evidence from quantitative sensory testing.

@article{Wang2012DoesLO,
  title={Does long-term opioid therapy reduce pain sensitivity of patients with chronic low back pain? Evidence from quantitative sensory testing.},
  author={Haili Wang and Christian Fischer and Gang Chen and Nina Weinsheimer and Simone Gantz and Marcus Schiltenwolf},
  journal={Pain physician},
  year={2012},
  volume={15 3 Suppl},
  pages={ES135-43}
}
BACKGROUND Long-term opioid treatment has been used extensively in treatment of chronic low back pain (cLBP) in the last decades. However, there are serious limitations to the long-term efficacy of opioids and related side effects. OBJECTIVES In this study we investigated whether long-term opioid treatment changes pain sensitivity of patients with cLBP. STUDY DESIGN A prospective, nonrandomized, cross-sectional study. SETTING Multidisciplinary pain management clinic, specialty referral… CONTINUE READING
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