Does lithium prevent relapse following successful electroconvulsive therapy for major depression? A systematic review and meta‐analysis

@article{Lambrichts2021DoesLP,
  title={Does lithium prevent relapse following successful electroconvulsive therapy for major depression? A systematic review and meta‐analysis},
  author={Simon Lambrichts and Johan Detraux and Kristof Vansteelandt and Axel Nordenskj{\"o}ld and Jasmien Obbels and Didier Schrijvers and Pascal Sienaert},
  journal={Acta Psychiatrica Scandinavica},
  year={2021},
  volume={143}
}
The risk of relapse following successful antidepressant treatment, including electroconvulsive therapy (ECT), is substantial. Lithium has been suggested to effectively prevent relapse, yet data remain limited and inconclusive. We performed a systematic review and meta‐analysis to examine the efficacy of continuation treatment with lithium in preventing relapse following a successful acute course of ECT in patients with major depression, in comparison to continuation treatment without lithium… Expand
2 Citations
Effectiveness of maintenance electroconvulsive therapy—Evidence from modifications due to the COVID‐19 pandemic
TLDR
This study strongly corroborates the effectiveness of c‐/m‐ECT in a real‐world population and indicates that patients with shorter time since index ECT seem to be at high risk for severe clinical deterioration in the case of treatment discontinuation or reduction. Expand
Relapse following bitemporal and high‐dose right unilateral electroconvulsive therapy for major depression
TLDR
Long-term outcome following high-dose right unilateral ECT does not differ from bitemporal ECT, and prognosis is particularly favourable in older adults, psychotic depression and patients maintained on lithium. Expand

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TLDR
There is strong evidence that lithium can help prevent relapses in the first 6 months after index ECT, however, there are several unanswered questions about its use post-ECT, including optimal target blood level, duration of use, and concomitant antidepressant choice. Expand
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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