Does insulin resistance co-exist with glucocorticoid resistance in the metabolic syndrome? Studies comparing skin sensitivity to glucocorticoids in individuals with and without acanthosis nigricans

Abstract

BACKGROUND The metabolic syndrome is associated with increased risk for both diabetes and coronary artery disease, which insulin resistance alone does not satisfactorily explain. We propose an additional and complementary underlying mechanism of glucocorticoid resistance. RESULTS Using acanthosis nigricans (AN) and skin vasoconstrictor (SVC) response to… (More)
DOI: 10.1186/1475-2840-11-31

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