Does genotype and equol-production status affect response to isoflavones? Data from a pan-European study on the effects of isoflavones on cardiovascular risk markers in post-menopausal women.

@article{Vafeiadou2006DoesGA,
  title={Does genotype and equol-production status affect response to isoflavones? Data from a pan-European study on the effects of isoflavones on cardiovascular risk markers in post-menopausal women.},
  author={Katherina Vafeiadou and Wendy Louise Hall and C. S. Williams},
  journal={The Proceedings of the Nutrition Society},
  year={2006},
  volume={65 1},
  pages={
          106-15
        }
}
The increase in CVD incidence following the menopause is associated with oestrogen loss. Dietary isoflavones are thought to be cardioprotective via their oestrogenic and oestrogen receptor-independent effects, but evidence to support this role is scarce. Individual variation in response to diet may be considerable and can obscure potential beneficial effects in a sample population; in particular, the response to isoflavone treatment may vary according to genotype and equol-production status… CONTINUE READING

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