Does genetic screening increase detection of familial medullary thyroid cancer in apparently sporadic cases?


DESIGN AND INTERVENTION This study enrolled individuals who presented with sporadic or hereditary MTC between 1993 and 2006. First-degree relatives of patients with hereditary disease were also invited to enroll. Genomic DNA was isolated from peripheral blood lymphocytes and subjected to genetic screening for RET mutations. Exons 10, 11, 13, 14, 15, and 16… (More)
DOI: 10.1038/ncpendmet0722