Does estrogen deficiency cause lacrimal gland inflammation and aqueous-deficient dry eye in mice?

Abstract

Researchers have proposed that estrogen deficiency will lead to a Sjögren's syndrome (SjS)-like lacrimal gland inflammation, aqueous tear deficiency and dry eye. The purpose of this study was to determine whether this proposal is correct. Lacrimal glands were obtained from adult, age-matched wild type (WT) and aromatase knockout (ArKO) mice, in which… (More)
DOI: 10.1016/j.exer.2014.07.017

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