Does delaying adjuvant chemotherapy after curative surgery for colorectal cancer impair survival? A meta-analysis.

@article{Guetz2010DoesDA,
  title={Does delaying adjuvant chemotherapy after curative surgery for colorectal cancer impair survival? A meta-analysis.},
  author={Ga{\"e}tan des Guetz and Patrick Nicolas and G Perret and J P Morere and Bernard Uzzan},
  journal={European journal of cancer},
  year={2010},
  volume={46 6},
  pages={1049-55}
}
BACKGROUND In stage III colorectal cancer (CRC), adjuvant chemotherapy (CT) is usually prescribed within two months after curative surgery. Whether or not delaying initiation of CT affects survival is still debated. MATERIAL AND METHODS We performed a meta-analysis (MA) of all published studies (full papers or abstracts) comparing delayed CT with standard care. Studies were obtained from a PubMed query (keywords: CRC, adjuvant treatment, delay of CT), a review (Chau et al., 2006), cross… CONTINUE READING