Does cryptic gluten sensitivity play a part in neurological illness?

@article{Hadjivassiliou1996DoesCG,
  title={Does cryptic gluten sensitivity play a part in neurological illness?},
  author={Marios Hadjivassiliou and A. Gibson and G Aelwyn B Davies-Jones and Alan Joseph Lobo and Timothy J. Stephenson and Anthony Milford-Ward},
  journal={The Lancet},
  year={1996},
  volume={347},
  pages={369-371}
}
Neurological Dysfunction in Coeliac Disease and Non-Coeliac Gluten Sensitivity
TLDR
The neurological manifestations of CD and NCGS are similar and equally responsive to a GFD suggestive of common pathophysiological mechanisms.
Neurological manifestations of celiac disease.
TLDR
CD should be ruled out in the differential diagnosis of neurological dysfunction of unknown cause, including ataxia, epilepsy and dementia, and a gluten free diet failed to improve the neurological disability.
Anti-ganglioside antibodies in coeliac disease with neurological disorders.
  • U. Volta, R. De Giorgio, F. Bianchi
  • Medicine, Biology
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • 2006
The high frequency of coeliac disease among children with neurological disorders
TLDR
It is unable, using indirect immunofluorescence testing, to demonstrate the presence of autoantibodies against brain tissue in CD and AGA‐positive patients, and whether this finding reflects certain immunopathogenic links between CD and particular neurological diseases needs to be studied.
Possible gluten sensitivity in multiple system atrophy
TLDR
The occurrence of gluten sensitivity in a population of MSA patients versus patients affected by idiopathic PD was studied, finding a high frequency in patients with certain neurologic syndromes of unknown etiology.
An investigation of the humoral immune response in patients with gluten ataxia.
TLDR
Preliminary findings suggest an immune pathogenesis for gluten ataxia, in common with other manifestations of gluten sensitivity, and preliminary evidence is also suggestive of a T-cell mediated response and the relative contributions of each in the pathogenesis of gluten atAXia remains to be elucidated.
Gluten-Related Disorders: Gluten Ataxia
TLDR
Evidence suggests that patients with newly diagnosed coeliac disease presenting to the gastroenterologists have abnormal MR spectroscopy at presentation associated with clinical evidence of subtle cerebellar dysfunction, which may protect the first group from the development and/or progression of neurological dysfunction.
Non-Celiac Gluten ( Wheat ) Sensitivity
TLDR
Most patients will stabilise or improve with strict adherence to gluten-free diet depending on the duration of the ataxia prior to the treatment, but all patients have spectroscopic abnormalities primarily affecting the vermis.
Neuropathy associated with gluten sensitivity
TLDR
Gluten sensitivity may be aetiologically linked to a substantial number of idiopathic axonal neuropathies associated with positive antigliadin antibodies in a cohort of patients with sporadic axonal Neuropathy.
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