Does cryptic gluten sensitivity play a part in neurological illness?

  title={Does cryptic gluten sensitivity play a part in neurological illness?},
  author={Marios Hadjivassiliou and A. Gibson and G Aelwyn B Davies-Jones and Alan Joseph Lobo and Timothy J. Stephenson and Anthony Milford-Ward},
  journal={The Lancet},
Neurological Dysfunction in Coeliac Disease and Non-Coeliac Gluten Sensitivity
The neurological manifestations of CD and NCGS are similar and equally responsive to a GFD suggestive of common pathophysiological mechanisms.
Neurological manifestations of celiac disease.
CD should be ruled out in the differential diagnosis of neurological dysfunction of unknown cause, including ataxia, epilepsy and dementia, and a gluten free diet failed to improve the neurological disability.
Anti-ganglioside antibodies in coeliac disease with neurological disorders.
  • U. Volta, R. De Giorgio, F. Bianchi
  • Medicine, Biology
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • 2006
The high frequency of coeliac disease among children with neurological disorders
It is unable, using indirect immunofluorescence testing, to demonstrate the presence of autoantibodies against brain tissue in CD and AGA‐positive patients, and whether this finding reflects certain immunopathogenic links between CD and particular neurological diseases needs to be studied.
Possible gluten sensitivity in multiple system atrophy
The occurrence of gluten sensitivity in a population of MSA patients versus patients affected by idiopathic PD was studied, finding a high frequency in patients with certain neurologic syndromes of unknown etiology.
An investigation of the humoral immune response in patients with gluten ataxia.
Preliminary findings suggest an immune pathogenesis for gluten ataxia, in common with other manifestations of gluten sensitivity, and preliminary evidence is also suggestive of a T-cell mediated response and the relative contributions of each in the pathogenesis of gluten atAXia remains to be elucidated.
Gluten-Related Disorders: Gluten Ataxia
Evidence suggests that patients with newly diagnosed coeliac disease presenting to the gastroenterologists have abnormal MR spectroscopy at presentation associated with clinical evidence of subtle cerebellar dysfunction, which may protect the first group from the development and/or progression of neurological dysfunction.
Non-Celiac Gluten ( Wheat ) Sensitivity
Most patients will stabilise or improve with strict adherence to gluten-free diet depending on the duration of the ataxia prior to the treatment, but all patients have spectroscopic abnormalities primarily affecting the vermis.
Neuropathy associated with gluten sensitivity
Gluten sensitivity may be aetiologically linked to a substantial number of idiopathic axonal neuropathies associated with positive antigliadin antibodies in a cohort of patients with sporadic axonal Neuropathy.


High prevalence of celiac disease in healthy adults revealed by antigliadin antibodies.
In the present study, a high IgA antigliadin activity had a positive predictive value between 18% and 25% in individuals without symptoms indicative of celiac disease depending on the way the cut-off points were chosen.
Compliance of adolescents with coeliac disease with a gluten free diet.
A cohort of 123 patients with coeliac disease, diagnosed in the first three years of life and followed up for at least 10 years, was reevaluated during the teenage period in terms of compliance with
Malignancy in coeliac disease--effect of a gluten free diet.
The results indicate that for coeliac patients who have taken a GFD for five years or more the risk of developing cancer over all sites is not increased when compared with the general population, and give further support for advising all patients to adhere to a strict G FD for life.
Celiac Disease and Malignancy
There was little evidence for the view that malignancy itself was the cause of the flat jejunal mucosal appearances seen in these patients, and the index of suspicion for lymphoma in celiac disease should be high and early laparotomy be considered in patients with unexplained deterioration.
Normal small bowel biopsy followed by coeliac disease.
Four patients (two children, one adolescent, and one adult) having normal small bowel mucosa shown on a biopsy specimen taken before the initial diagnosis of coeliac disease was made may exist latent in patients having normal mucosa when eating a normal diet containing gluten.
Biopsy pathology of the small intestine
When you read more every page of this biopsy pathology of the small intestine, what you will obtain is something great.
The natural history of gluten sensitivity: defining, refining and re-defining.
  • M. Marsh
  • Medicine
    QJM : monthly journal of the Association of Physicians
  • 1995
Anti-gliadin antibodies.