Does cortical thinning in persons at increased risk for major depression also increase their risk for Alzheimer's disease?

@article{Pomara2009DoesCT,
  title={Does cortical thinning in persons at increased risk for major depression also increase their risk for Alzheimer's disease?},
  author={Nunzio Pomara and John J. Sidtis},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 29},
  pages={E82; author reply E83}
}
Peterson et al. (1) hypothesized a possible role of right hemisphere thinning in increasing the risk for depressive illness in biological descendants (children or grandchildren) of individuals with recurrent familial major depression (MDD). They also noted that the 28% reduction in cortical thickness that they observed in this population rivaled the magnitude of cortical thinning which has been reported in some neuropsychiatric disorders including Alzheimer’s disease (AD). Thinning of the… CONTINUE READING

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