Does clozapine decrease smoking?

@article{Leon2005DoesCD,
  title={Does clozapine decrease smoking?},
  author={Jos{\'e} De Leon and Francisco J D{\'i}az and Richard C. Josiassen and Thomas B. Cooper and George M. Simpson},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2005},
  volume={29},
  pages={757-762}
}
McEvoy et al.'s study in 1999, which used cotinine levels but had limited power, suggested that clozapine treatment may be associated with a mild smoking decrease (particularly when plasma clozapine levels are > 150 ng/ml). Some naturalistic studies also suggest that clozapine treatment may be associated with a mild smoking decrease. The present study included 38 schizophrenic daily smokers from a double-blind clozapine trial. Five analyses were tested for significant decreases in plasma… CONTINUE READING

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