Does clinical equipoise apply to cluster randomized trials in health research?

@inproceedings{Binik2011DoesCE,
  title={Does clinical equipoise apply to cluster randomized trials in health research?},
  author={Ariella Binik and Charles Weijer and Andrew D. McRae and Jeremy M. Grimshaw and Robert F. Boruch and Jamie C. Brehaut and Allan Donner and Martin Paul Eccles and Raphael Saginur and Monica Taljaard and Merrick Zwarenstein},
  booktitle={Trials},
  year={2011}
}
This article is part of a series of papers examining ethical issues in cluster randomized trials (CRTs) in health research. In the introductory paper in this series, Weijer and colleagues set out six areas of inquiry that must be addressed if the cluster trial is to be set on a firm ethical foundation. This paper addresses the third of the questions posed, namely, does clinical equipoise apply to CRTs in health research? The ethical principle of beneficence is the moral obligation not to harm… CONTINUE READING