Does chronic hypoxaemia induce transformations of fibre types?

@article{Hildebrand1991DoesCH,
  title={Does chronic hypoxaemia induce transformations of fibre types?},
  author={I L Hildebrand and Christer Sylven and Mona Esbj{\"o}rnsson and Karin Hellstr{\"o}m and Eva K. Jansson},
  journal={Acta physiologica Scandinavica},
  year={1991},
  volume={141 3},
  pages={435-9}
}
The study comprised nine patients with chronic obstructive lung disease. Quadriceps muscle biopsies were studied with respect to fibre type composition before and after haemodilution that brought haemoglobin (Hb) to within normal limits. Ten days elapsed between the two biopsy occasions. The arterial oxygen tension (PaO2) and saturation (SaO2) were depressed to 8.4 +/- 2.0 kPa and 89 +/- 11% in the patients with chronic obstructive lung disease and increased to 9.2 +/- 2.1 and 91 +/- 8% with… CONTINUE READING

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