Does breast feeding help protect against atopic disease? Biology, methodology, and a golden jubilee of controversy.

@article{Kramer1988DoesBF,
  title={Does breast feeding help protect against atopic disease? Biology, methodology, and a golden jubilee of controversy.},
  author={Michael S Kramer},
  journal={The Journal of pediatrics},
  year={1988},
  volume={112 2},
  pages={
          181-90
        }
}
To help shed some light on the 50-year-old controversy concerning the possible protective effect of breast feeding on subsequent atopic disease, I developed 12 standards pertaining to both biologic and methodologic aspects of exposure (infant feeding), outcome (atopic conditions), and statistical analysis for studies of atopic eczema, asthma, allergic rhinitis, cow milk allergy, and other food allergy. Among the published studies on atopic eczema, the nine claiming a protective benefit of… CONTINUE READING
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